Editorial .......................................................................................................................................1
Původní práce
Miloslav Kopeček, Klára Látalová, Dagmar Dvořáková, Simona Papežová,
Markéta Zemanová, Jan Tuček, Pavel Mohr
Stručný kognitivní test (SCOT): skríninkový nástroj k měření kognitivního postižení u pacientů
se schizofrenií a bipolární afektivní poruchou (pilotní data)..................................................................... 5

Přehledné články
Ľubomíra Izáková, Daniela Ježová
Aldosterón – nový biologický marker alebo ďalšia možnost v liečbe depresie? .......................................13
Anna Kubešová, Jiří Horáček
Vliv psychotropních látek na neurogenezi v dospělém savčím hipokampu .............................................19
Aleš Bartoš, Pavel Martínek, Daniela Řípová
Hodnocení soběstačnosti u pacientů s mírnou kognitivní poruchou a demencí .......................................23
Vzdělávání
Pavel Theiner, Tomáš Kašpárek, Alena Fiľová
Hyperkinetická porucha (ADHD) .......................................................................................................27
Fórum české neuropsychofarmakologické společnosti
Martin Anders, Jakub Albrecht
Nové antidepresivum s multimodálním mechanizmem účinku – vortioxetin (Lu-AA21004) ......................35
Zprávy ...........................................................................................................................................43
Přečetli jsme za vás .......................................................................................................................48
Dopisy, ohlasy, diskuze ..................................................................................................................50
Nové knihy ....................................................................................................................................52

CONTENTS

Forum of the Czech Neuropsychopharmacological Society
Martin Anders, Jakub Albrecht
A novel multimodal antidepressant compound – vortioxetine (Lu-AA21004) ..........................................35
News ............................................................................................................................................43
We have read for you ..................................................................................................................... 48
Letters, response, discussion .........................................................................................................50
New Books ................................................................................................................................... 52

Editorial
František Jelínek........................................................................1

PŘEHLEDNÉ ČLÁNKY
Intratracheální mycetom u psa. Kazuistické sdělení
Pavel Mužík, František Čada.......................................................9
Možnosti digitální radiografie
Martin Zelinka...........................................................................14
PŘEKLADOVÉ ČLÁNKY
Terapie antibiotiky, aktualizace pro medicínu malých zvířat – 1. díl
Jörg W. Schäffer........................................................................29
FOTOGALERIE
Tamara Sobalová.......................................................................38

Abstrakta ze zahraničních časopisů...........................................42
Bioptická kazuistika
Souběžný výskyt rektálního papilotubulárního adenomu
(kolorektálního polypu) a diferencovaného karcinomu rekta u psa
František Jelínek, Jiří Michálek..................................................50
ZPRÁVY
Zde informuje Státní veterinární správa ČR
Josef Duben..............................................................................54
Informace z Českého svazu ochránců přírody
Petr Stýblo...............................................................................58
Zde informuje Státní veterinární správa ČR
Josef Duben.............................................................................62

Editorial
František Jelínek...........................................................................1

REVIEWS
Intratracheal mycetoma in a dog. A case report
Pavel Mužík, František Čada..........................................................9
Digital radiographic artifacts
Martin Zelinka...............................................................................14
TRANLATED WORKS
Therapy with antibiotics, update for medicine of small animals – first part
Jörg W. Schäffer.................................................................................29
PHOTOGALLERY
Tamara Sobalová................................................................................38

Abstracts from foreign journals.............................................................42
BIOPTIC CASE REPORT
The Simultaneous Occurence of Rectal Papillotubular Adenoma
(Colorectal Polyp) and Well Differentiated Rectal Carcinoma in a Dog
František Jelínek, Jiří Michálek.............................................................50
NEWS
Here informs the State veterinary management in the Czech Republic
Josef Duben.......................................................................................54
Information from the Czech Union for Nature Conservation
Petr Stýblo........................................................................................58
Here informs the State veterinary management in the Czech Republic
Josef Duben.......................................................................................62

Editorial
Václav Špičák, Vít Petrů.............................................................................................................1

PŮVODNÍ PRÁCE
Asociácia polymorfizmov v géne pre transformujúci rastový
faktor-β1 s atopickou asthma bronchiale
Juraj Javor, Martin Dzurilla, Mojmír Vrlík, Magda Suchánková, Mária Bucová, Milan Buc....................9
Studie zdravotního stavu dětí v Ostravě 2001–2009
Miroslav Dostál, Anna Pastorková, Vlasta Švecová, Radim J. Šrám................................................16

PŘEHLEDNÉ ČLÁNKY
Eosinofilní stavy etiopatogeneze, klasifikace, diagnóza a léčba
Martina Vašáková......................................................................................................................30
Suché oko
Katarína Hlaváčková...................................................................................................................37

FARMAKOTERAPIE, IMUNOTERAPIE

DIAGNOSTIKA A LABORATORNÍ TECHNIKA
Komplementový systém a jeho laboratorní diagnostika
Jan Martinek, Ivo Lochman..........................................................................................................55
In vitro diagnostika hypersenzitivních reakcí vyvolaných léky
Lenka Sedláčková......................................................................................................................62

DISKUSNÍ  FÓRUM
Petr Čáp....................................................................................................................................69
Petr Čáp....................................................................................................................................69
Jaromír Bystroň..........................................................................................................................70
Petr Pohunek.............................................................................................................................73
INFORMACE..............................................................................................................................75
REJSTŘÍKY supplementum 2012..................................................................................................80

Editorial
Václav Špičák, Vít Petrů..................................................................................................................1
ORIGINAL PAPERS
Association of polymorphisms in the gene encoding transforming
growth factor-β1 with atopic asthma bronchiale
Juraj Javor, Martin Dzurilla, Mojmír Vrlík, Magda Suchánková,
Mária Bucová, Milan Buc...................................................................................................................9
The follow up of children health in Ostrava 2001–2009
Miroslav Dostál, Anna Pastorková, Vlasta Švecová, Radim J. Šrám.....................................................16
REVIEWS
Eosinophilic disorders ethiopathogenesis, classification, diagnosis and treatment
Martina Vašáková.............................................................................................................................30
Dry eye
Katarína Hlaváčková.........................................................................................................................37
FARMAKOTHERAPY, IMUNOTHERAPY
Monitoring to asses effectiveness of sublingual allergen immunotherapy

by administration of Staloral 300 depending on compliance
Jaromír Paukert, Eliška Kopelentová, Martina Králová,
Marie Charvátová, Marie Paukertová, Šárka Dobiášová,
Klára Kruntorádová............................................................................................................................41
COMBAIR – change of view?
Václav Špičák...................................................................................................................................51
DIAGNOSTIC AND LABORATORY TECHNIQUE
The complement system and its laboratory diagnostics
Jan Martinek, Ivo Lochman.................................................................................................................55
In vitro diagnosis of drug hypersensitivity reactions
Lenka Sedláčková..............................................................................................................................62
DISCUSSION FORUM
Petr Čáp.........................................................................................................................................69
Petr Čáp........................................................................................................................................69
Jaromír Bystroň..............................................................................................................................70
Petr Pohunek.................................................................................................................................73
INFORMATION...............................................................................................................................75
INDEX supplementum 2012..............................................................................................................80

Editorial ...............................................................................................................................1
Program ...............................................................................................................................4

Plenární přednášky
prof. Dr. Hans-Ulrich Wittchen ................................................................................................11
prof. Jan Volavka, MD, PhD. ...................................................................................................11
prof. ThDr. Otakar A. Funda, Dr. Theol......................................................................................11

Odborná sympozia
Sympozium Společnosti pro biologickou psychiatrii:
Abnormní pohyby v psychiatrii a neurologii .............................................................................12
Terapeutické implikace klinicko-patologických korelací neurodegenerativních onemocnění ..........13
Antipsychotika .....................................................................................................................14
Personalizovaná léčba psychofarmaky ...................................................................................16
Sympozium České a Slovenské psychiatrické společnosti:
Farmakoterapie psychický poruch – záleží na pohlaví? ............................................................16
EPIGENOM – nové interpretační možnosti genetiky ................................................................18
Antidepresiva ...................................................................................................................... 19
Thymoprofylaktika ................................................................................................................21
Psychofarmaka v sexuologii ..................................................................................................22
Význam endokanabinoidního sytému u psychiatrických poruch a jejich léčení........................... 23
Anxiolytika – od mechanizmu účinku k praxi.......................................................................... 24
Farmakoterapie a psychoterapie – spolu nebo zvlášť?............................................................. 26
Obsedantně kompulzivní porucha – od psychopatologie k léčbě ...............................................28
Ketamin: Léčebné a výzkumné využití v psychiatrii...................................................................29
Možnosti predikce individuálního průběhu schizofrenie .............................................................31
Personalizované přístupy v diagnostice a léčbě Alzheimerovy choroby ..................................... 32
SETKÁNÍ S ODBORNÍKEM
doc. MUDr. Eva Malá, CSc. ..................................................................................................34
prim. MUDr. Michal Maršálek, CSc. .......................................................................................34
prof. MUDr. Cyril Höschl, DrSc., FRCPsych. ......................................................................... 34
PRACOVNÍ SNÍDANĚ ČNPS
Terapeutické monitorování psychofarmak – význam pro klinickou praxi .....................................35
Nový výzkum
Nový výzkum – Preklinický výzkum .......................................................................................37
Nový výzkum – Klinický výzkum I ..........................................................................................39
Nový výzkum – Klinický výzkum II ........................................................................................ 41
Workshopy
Komplexní přístup v léčbě hraniční poruchy osobnosti..............................................................43
Sedmero hlavních hříchů – Závist ...........................................................................................44
Komplexní léčba úzkostných poruch ......................................................................................46
Diferenciální diagnostika a farmakoterapie demencí III ..............................................................48
Neuropsychiatrické omyly, alarmující příběhy z praxe ............................................................. 48
Vývěsková sdělení
Vývěsková sdělení – Preklinické studie ..................................................................................49
Vývěsková sdělení – Klinické studie....................................................................................... 55
Vývěsková sdělení – Cholinergní neurotransmise, léčba Alzheimerovy choroby ..........................64
Firemní sympozia .................................................................................................................70
Jmenný rejstřík ................................................................................................................... 71

CONTENTS

Editorial................................................................................................................................ 1
Programme............................................................................................................................4
PLENARY LECTURES
prof. Dr. Hans-Ulrich Wittchen ...............................................................................................11
prof. Jan Volavka, MD, PhD. ................................................................................................. 11
prof. ThDr. Otakar A. Funda, Dr. Theol. ...................................................................................11
SCIENTIFIC SYMPOSIA
Abnormal movements in psychiatry and neurology
(Symposium of the Society of Biological Psychiatry) ..............................................................12
Clinico-pathological correlations in neurodegenerative dementias
and their treatment implications ............................................................................................13
Antipsychotics ....................................................................................................................14
Personalized treatment with psychotropic drugs .....................................................................16
Pharmacotherapy of psychic disorders – does the gender matter?
(Sympozium of Czech and Slovak Psychiatric Society) ...........................................................16
The role of endocannabinoid system in psychiatric disorder and their treatment .........................18
EPIGENOM – new aspects for interpretation in genetics ..........................................................19
Antidepressants ...................................................................................................................21
Mood stabilizers ..................................................................................................................22
Psychotropic drugs and sexology ..........................................................................................23
Anxiolytics – from the mechanism of action to the practise ......................................................24
Pharmacotherapy and psychotherapy – together or separately .................................................26
Obsessive compulsive disorder – from psychopathology to the treatment ..................................28
Ketamine: Treatment and research use in psychiatry ..............................................................29
Prediction of individual course of schizophrenia – ways and possibilities ...................................31
Personalized approach in diagnostic and treatment of Alzheimer disease .................................32
MEET THE EXPERT
doc. MUDr. Eva Malá, CSc. ..................................................................................................34
prim. MUDr. Michal Maršálek, CSc. .......................................................................................34
prof. MUDr. Cyril Höschl, DrSc., FRCPsych. ..........................................................................34
ČNPS BREAKFAST SYMPOSIA
Therapeutic monitoring of psychotropic drugs – relevance to clinical practise ............................35
NEW RESEARCH
New research – Preclinical research .....................................................................................37
New research – Clinical research I ........................................................................................39
New research – Clinical research II ........................................................................................41
WORKSHOPS
Complex approach to the patients with borderline personality disorder ......................................43
Seven deadly sins – Envy ....................................................................................................44
Complex treatment of anxiety disorders ................................................................................46
Differencial diagnosis and pharmacotherapy of dementias ......................................................48
Neuropsychiatric mistakes – alarming stories from clinical practice......................................... 48
POSTER SESSIONS
Poster sessions – Preclinical research .................................................................................49
Poster sessions – Clinical research ......................................................................................55
Poster sessions – Cholinergic neurotransmission, treatment of Alzheimer disease .................. 64
SPONSORED SATELLITE SYMPOSIA ................................................................................70
NAME INDEX .....................................................................................................................71